An alternative method.
Look at
FullForm[eq1]
and find the exact form your expression appears in. This may be different from the displayed form, particularly when there are denominators or negative exponents. Copy the exact form from the FullForm into your replacement pattern like these which I found in your eq1:
eq2 = eq1 /. {Power[Times[Dp, s], Rational[-1, 2]] -> 1/(Sqrt[Dp]*Sqrt[s]),
Power[Times[Dp, s, Plus[s, \[Theta]c]], Rational[-1, 2]] -> 1/(Sqrt[Dp] Sqrt[s] Sqrt[s + \[Theta]c]),
Power[Times[Power[Dp, -1], s], Rational[-1, 2]] -> 1/(Sqrt[s]/Sqrt[Dp])}
The precise format of the right hand side of each replacement rule is not as critical as the left hand side.
This method often takes more work, but will sometimes succeed when trying again and again to find a way to make the substitution work has failed.
After the substitution there may be automatic changes to the format before it is displayed. It is even possible that the automatic changes may undo your some or all of your substitutions, like if you wanted to substitute 7*7 for 49 or x*x for x squared or other less obvious things.