Why would you expect the indefinite integral to have a closed form?
In[1]:= int = Integrate[Sqrt[x] Exp[-(x - 1)^2], {x, 0, Infinity}]
Out[1]= (Gamma[3/4] Hypergeometric1F1[3/4, 1/2, 1] + 2 Gamma[5/4] Hypergeometric1F1[5/4, 3/2, 1])/(2 E)
In[2]:= N[int, 50]
Out[2]= 1.6436165407874952730553651165549411806023882736885