Thank you Jos! The issue appears when you have magnification set greater than 100%.

Thank you for the help with the example image option. I wasn't aware of that. This gives me something to play with.

I was hoping to find an option that would allow me to disable the default image, and instead default to the image you get after the graph is clicked. This would solve my problem, as I have many animations with many different sizes.

Hi Mike,

I don't see the problem on my machine. MM10.2. - Windows 7 But you can set as example the ImageSize->{100,200}.

Axis3D[a_, b_, c_, d_, e_, f_] := 
 Show[Graphics3D[{Arrowheads[.02], Arrow[{{0, 0, e}, {0, 0, f}}]}], 
  Graphics3D[{Arrowheads[.02], Arrow[{{0, c, 0}, {0, d, 0}}]}], 
  Graphics3D[{Arrowheads[.02], Arrow[{{a, 0, 0}, {b, 0, 0}}]}], 
  Graphics3D[{Text["\!\(\*
     StyleBox[\"x\",\nFontWeight->\"Plain\"]\)", {b*1.1, 0, 0}], 
    Text["y", {0, d*1.1, 0}], Text["z", {0, 0, f*1.1}]}], 
  Boxed -> False,
  ImageSize -> {100, 200},
  ViewPoint -> {8, 4, 4}, ViewVertical -> {0, 0, 1}]
Axis3D[0, 3, 0, 3, 0, 9]