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Gürkan Sin is a Professor in Process Systems Engineering (PSE) at DTU Chemical Engineering, Technical University of Denmark, Lyngby.
Dr. Sin holds BSc and MSc degrees (2000) from Middle East Technical University (METU), Turkey, and a PhD (2004) from Ghent University, Belgium.
Research Interests: Prof. Sin's research centers on analyzing and synthesizing process systems for bio/pharmaceutical, renewable fuels, and chemicals (biorefinery, power-to-X) and water treatment. He develops methods to guide decision-making from R&D and scale-up to design and operation, with a current focus on emerging AI and computing technologies for sustainable process industries. His research has focused on the fundamental limitations and challenges of deterministic approaches in PSE applications—such as the inability of the models in predicting impurity formation in bioprocesses, uncertainty in predicting techno-economic feasibility of new process concepts, among others due to incomplete knowledge and computational irreducibility, and conceiving methodologies employing via negativa principle to guide truthful engineering solutions.

Funding and Leadership: Prof. Sin has secured over €15 million in competitive funding from Danish, European, and industry sources aiming at expanding interdisciplinary applications of PSE methods for better engineering decision making. He has coordinated large-scale EU Horizon projects like Modlife ITN (training of 15 PhD candidates for life science industries) and PROSAFE DN (training of 12 PhD candidates in AI-PSE for sustainable renewable energy transition), driving multidisciplinary collaboration in understanding process systems complexity and expanding engineering toolbox for PSE professionals. Key Outcomes: Prof. Sin has trained over 35 PhDs, 14 postdocs, and numerous MSc students in interdisciplinary applications of PSE in particular life science industries. His group has produced ~350 peer-reviewed publications, with +7000 citations and an h-index of 43 (Scopus, November 2025).