It is not in general possible (at this point) to call WL functions from SystemModeler components.
I agree that it would be a great feature to have.
What you can currently do is use functions that are simple enough to be converted to Modelica (the language used by SystemModeler models) in CreateSystemModel:
model = CreateSystemModel[{Unevaluated[Function[#1 + Sin[#2]]][1,
u[t]] == u'[t]}, t]
The Scope section of the CreateSystemModel reference page has an overview of what is currently supported.