Some of those can be handled with FontVariations. Letter spacing can be handled with FontTracking. You might want to look into Stylesheets. I don't really have depth of knowledge in this stuff, so hopefully someone else will chime in.

There is a way to orient a Text expression. Look at the documentation for Text, specifically the optional fourth argument for orientation.

But I suspect that this is not what you're asking about. If you're asking about localizing a notebook (or even just a string) to use a language that reads right to left, then I don't know how to do that. I played around a bit with the unicode right-to-left marker, and it doesn't seem to have any effect.

If this is indeed not supported, then that's very disappointing. It might be worth asking customer support. I'd love to get an update if you discover anything.