Yes, it is possible to sync a local folder with a folder located in the Wolfram Cloud. Wolfram Cloud provides a feature called "CloudDirectory" that allows you to interact with cloud-based directories and files.
Here's a general outline of the steps you can follow to sync a local folder with a Wolfram Cloud folder:
Upload your local folder to the Wolfram Cloud: You can use the CloudUpload function in Mathematica to upload the contents of your local folder to the cloud. For example:
CloudUpload["/path/to/local/folder", CloudObject["path/to/cloud/folder"]]