I've also been trying call Python from MMA 10.0.2. I've been trying to use the StartProcess command to start a python interpreter and then use WriteBinary and ReadString to the process' stdin, stdout and stderr. However not really with any success. The trivial examples in the documentation with 'cmd' do work but I haven't been able to build on them.
Your success with Pythonika is encouraging, I'll give that a go.