I suppose you know that all of the following statements are true:
Binomial[-1, 0] == 1
Binomial[-1, 1] == -1
Binomial[-1, 2] == 1
Binomial[-1, 3] == -1
Binomial[-1, 4] == 1
So while I don't know why you would want to change the usual definition, you could always use a replacement rule at the end of your calculations:
x + 2 Binomial[-1, m] /. Binomial[-1, m_] -> -1
(* -2+x *)