Message Boards Message Boards

GROUPS:

[Notebook] Geometrical analysis of genome for COVID-19 vs SARS-like viruses

Posted 10 months ago
3479 Views
|
1 Reply
|
5 Total Likes
|

Z-curve theory provides a very unique geometrical approach of analyzing a genetic sequence, while preserving all the genome information. In this computational essay, I've developed a very efficient and fast function (in the Wolfram Language) to generate the Z-curve of any genetic sequence, regardless of its length. Then, I generate Z-curves of 39 COVID-19 viruses together with 40 SARS-like viruses, using their complete genomes. Numerical analysis of corresponding Z-curves and their clustering show a very close phylogenetic relationship between family of COVID-19 viruses and Bat coronavirus isolate RaTG13 (MN996532), therefore supporting the hypotheses of a Bat origin for the COVID-19.

enter image description here - Congratulations! This post is now featured in our Staff Pick column as distinguished by a badge on your profile of a Featured Contributor! Thank you, keep it coming, and consider contributing your work to the The Notebook Archive!

Reply to this discussion
Community posts can be styled and formatted using the Markdown syntax.
Reply Preview
Attachments
Remove
or Discard

Group Abstract Group Abstract