Message Boards Message Boards

[Notebook] Geometrical analysis of genome for COVID-19 vs SARS-like viruses

Z-curve theory provides a very unique geometrical approach of analyzing a genetic sequence, while preserving all the genome information. In this computational essay, I've developed a very efficient and fast function (in the Wolfram Language) to generate the Z-curve of any genetic sequence, regardless of its length. Then, I generate Z-curves of 39 COVID-19 viruses together with 40 SARS-like viruses, using their complete genomes. Numerical analysis of corresponding Z-curves and their clustering show a very close phylogenetic relationship between family of COVID-19 viruses and Bat coronavirus isolate RaTG13 (MN996532), therefore supporting the hypotheses of a Bat origin for the COVID-19.

POSTED BY: Mads Bahrami

enter image description here - Congratulations! This post is now featured in our Staff Pick column as distinguished by a badge on your profile of a Featured Contributor! Thank you, keep it coming, and consider contributing your work to the The Notebook Archive!

POSTED BY: Moderation Team
Reply to this discussion
Community posts can be styled and formatted using the Markdown syntax.
Reply Preview
Attachments
Remove
or Discard

Group Abstract Group Abstract