I've looked at the advanced guide on this and have a small question.
In the specification of Manipulate there has to be an expression/s and there has to be a variable/s or Control/s. Either of these can be wrapped in  Row or Column - see my source code example.
However I am wondering if there is anyway to wrap both the expression and the variable part under  a single Column (say)? 
If I alter my source so the Row statement sits within the Column statement, rather than after, then the system complains of a missing variable section.
The reason I would like to do this is to have maximum control over both controls and plots using the Grid family.