Crossposted here.

Do you want to directly run your notebook? A "wolfram file" is ambiguous. You could set some global variables to change parameters and then iterate over NotebookEvaluate@NotebookObject[] where the object is found by running EvaluationNotebook[] in the notebook you want to run or by pointing at the file path. of the notebook you want to run many times. You could also save your notebook as a .wl script which you can run with commend line arguments. Or what I usually do when I have a notebook full of good cells is that I will move all the code into a big function definition so I can iterate over it. Or define each cell as a setdelayed variable by placing varName:= in the front. Honestly this refactoring process is a bit laborious. Ha, you know what the issue is, you want a notebook to script converter like jupyter has... yeah... Or you could also do some crazy madness using TemplateNotebook@NotebookRead@InputNotebook[] lol madness