Thank you for your comments.
My original equation is
y = Sum_{i=0}{N} (v[i] - v0/Xs * (Xs - x[i])^3)^2
First, I get the differential for the Xs variable
y1 = D[y,Xs]
Then, I'd like to solve the above equation for Xs by using Solve command:
Solve[y1,Xs,Reals]
I also try to solve the original equation by hand, however i still got the final result because it is to complicated long equation.
I would greatly appreciate any help you can give me in working this problem.