Assumptions is an option. If an option is repeated, only the first one is used, the rest are ignored. E.g. compare
Plot[Sin[x], {x, 0, 2 Pi}, PlotStyle -> Thick, PlotStyle -> Dashed]
Plot[Sin[x], {x, 0, 2 Pi}, PlotStyle -> Dashed, PlotStyle -> Thick]
Combine the Assumptions. E.g.
Integrate[1/(x (r - x)), {x, Ra, Rs},
Assumptions ->
Element[x | r | Ra | Rs, Reals] && 0 < Ra < Rs && r > Rs && r > Ra]