You could write
f[x_] := x^2 - x + 3;
Plot[#[[2]], {x, -6, 6}, PlotRange -> 15, PlotStyle -> #[[1]]]
& /@ {{Red, f[x]}, {Green, f[2 x]}, {Blue, f[x - 2]}, {Orange, -2 f[x]}}
as well, if you prefer to use /@ instead @@@. /@ is the shortcut for Map[ ] and applies the function to each element of first level in the list. Here each of these elements will be a list again such as{Red, f[x]}.
By the way: Simply writing #1 and #2 won't be succesfull. You need the subscription given by the brackets [[ ]].