Wolfram has just released a Mathematica 10.4.1 update that fixes critical issues identified in 10.4.0, including a code signing (Gatekeeper) bug that surfaced with Apple's Mac OS X 10.11.4 update, OpenGL issues introduced in the 10.4.0 upgrade, and activation problems on Linux reported by a few customers.
Eligible customers will receive 10.4.1 update notifications from us over the next few days.
You can get additional details about this release on the Mathematica Quick Revision History page: http://www.wolfram.com/mathematica/quick-revision-history.html